03-05-2014, 12:31 AM
Lotus your NBE program looks good. I've tried PM and find it wasn't as strong as Estrogel, the gel really works, and bypasses the liver atleast the first time around.
"Oral preparations are not necessarily predictably absorbed, and are subject to a first pass through the liver, where they can be metabolized, and also initiate unwanted side effects. Therefore, alternative routes of administration that bypass the liver before primary target organs are hit have been developed. Transdermal and transvaginal routes are not subject to the initial liver passage."
http://en.wikipedia.org/wiki/Estradiol
"Oral preparations are not necessarily predictably absorbed, and are subject to a first pass through the liver, where they can be metabolized, and also initiate unwanted side effects. Therefore, alternative routes of administration that bypass the liver before primary target organs are hit have been developed. Transdermal and transvaginal routes are not subject to the initial liver passage."
http://en.wikipedia.org/wiki/Estradiol