[Eloise]

If there's one certitude of PM usage, it's that the effects, both mental and physical, differ person-to-person. Some people here have reported no mental effects while having all the physical effects; some reported mental effects before having any physical effects; and some even reported no mental or physical effects. There's only one way to really find out how PM will work on you: you have to take it. But you shouldn't take PM lightly. It's more than just popping some caps.

Which brings me to the point: It would seem that since PM is a phytoestrogen (that is, it mimics estrogen (E2)), its mental effects should only happen when you take PM. Once you stop PM, any PM-induced mental effects should stop. The physical effects (ie, boobs), however, are a bit more permanent. (This is a question best answered by Lotus.)

I'm not a doctor, so I can't give you a fool-proof 100% answer.