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Is PM an anti-androgen?
#2

(06-03-2014, 03:29 PM)ClaraKay Wrote:  Mistress Lotus has taught us that herbs including Saw Palmetto, Spearmint, Pygeum, Licorice root, and White Peony are anti-androgens, that is, they inhibit the production of testosterone in our bodies. Shouldn't Pueraria Mirifica (PM) be included in the list?

I recently had my total T tested and found that it is very low -- near the high end of the testosterone range for a bio-woman. This was accomplished by taking PM. Okay, I admit I took 800 mg of Spearmint daily for three weeks and 200 mg of Pygeum daily for two weeks, but stopped taking those 10 days before my test, so I doubt they had much effect on my T.

For me at least, PM seems to have acted as an effective anti-androgen as well as flooding my body with miroestrol, the estradiol mimic, which triggered breast growth.




Given the dual function of PM, it makes sense that beginners to NBE limit their regimen to just PM. After a couple of months have their total T tested to see if it needs to be forced down further using one of the other AAs.

If you agree the PM is also an anti-androgen, how does it work as such? Why is one's T level getting reduced? Is PM anti-5 alpha reductase? My DHT was certainly lowered as evidenced by my scalp hair regrowth. Does it bind up testosterone making it unavailable to the cells?

Okay, hit me with your best shot, but be gentle, girls. Big Grin

Clara Smile

Yes, its a minor anti-androgen, PM has several coactivatiors, one being (daidzien).

Daidzein (Isoflavonoid) acts as an anti-androgen by modulating androgen receptor coactivators in the prostrate. And then it acts as a phytoandrogen to the androgen receptors that plays an important part in the prostrate.

So considering that PM has 15 different derivatives and only one is an androgen, I'd say that's minor.



By modulating androgen receptor coactivators, daidzein may act as a phytoandrogen.
(PMID:17252558)
http://europepmc.org/abstract/MED/17252558/reload=0;jsessionid=A98DMTUQGThN7NZ8q0pd.2



By modulating androgen receptor coactivators, daidzein may act as a phytoandrogen
http://onlinelibrary.wiley.com/doi/10.1002/pros.20470/abstract;jsessionid=CB374D9A89B74EE19CA275F4FA69E7BF.f04t01


Anything else I'll catch later, can't keep eyes open
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Messages In This Thread
Is PM an anti-androgen? - by GoneGirl - 06-03-2014, 03:29 PM
RE: Is PM an anti-androgen? - by Lotus - 07-03-2014, 06:14 AM
RE: Is PM an anti-androgen? - by Lotus - 07-03-2014, 07:46 AM
RE: Is PM an anti-androgen? - by GoneGirl - 07-03-2014, 08:22 PM
RE: Is PM an anti-androgen? - by Lotus - 07-03-2014, 09:45 PM
RE: Is PM an anti-androgen? - by wantingmore72 - 07-03-2014, 10:24 PM
RE: Is PM an anti-androgen? - by Lotus - 07-03-2014, 11:35 PM
RE: Is PM an anti-androgen? - by Lotus - 07-03-2014, 11:51 PM
RE: Is PM an anti-androgen? - by Pansy-Mae - 08-03-2014, 07:18 AM



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