[GoneGirl]

DHT blockers will also artificially inflate your total T, since it prevents T from binding at DHT receptors and is still free in the bloodstream and measured as total T.

About whether your T will rise from taking PM/Estradiol/PC...I highly doubt it. Not so much because of the very mild AA effect of PM, but because T is already on the low end, so once you boost the E up your body will make even less T in response. So it has more to do with the endocrine system's natural feedback loop to keep hormones in balance than it does the mild AA effect.

Although, the lack of a DHT blocker could possibly result in enough of that being made to bother you, even if the total T is lower. You'll know if that's the case soon enough. If you start getting horny/irritable, add one.

I think I understand what you've said, Sarah. It's true that PM is not a T-blocker, but it still lowers one's T levels indirectly and, in my case, drastically. My Total T was recently measured at a very low 109 ng/dl from essentially PM alone. Sorry, I don't have a number for my free T.

I'm pretty sure that most endocrinologists know little about herbal estrogenics and T-blockers, so a patient like any one of us is going to throw them off. The only reason I can think of to switch to synthetic estrogen is that it will react with more kinds of estrogen receptors than miroestrol, and it's more potent. As for breast growth, miroestrol interferes with estradiol, thus blunting its effect. That's good for lowering the risk of getting breast cancer.

I think that if I ever got to the point that I wanted to go the pharma route, I would drop the herbals altogether and take spiro/estrogen/progesterone like most transsexuals do. At least then the endos know what they're dealing with.

Hey, I'm not an herbal purist, just trying to be practical.

Clara