[Lotus]

So some surprising facts:

This is just to show the differences to NBE and using real hormones:

Feminizing Hormone Regimens

If you have access to laboratory testing, a serum estradiol level of about 125-200 pg/ml – about one-third to one-half the normal female mid-cycle peak – is often considered ideal, at least for the first two years or so of feminizing therapy. It is not necessary or desirable to "cycle" estrogen, or any other medication, in an attempt to mimic the normal female menstrual cycle.

If you have access to laboratory testing, a serum testosterone level within the normal female range – about 5-85 ng/dl for total testosterone, or 0.1–2.2 pg/ml for free testosterone – is usually considered ideal. Within the female normal range, lower numbers are not necessarily better.
http://annelawrence.com/regimens.html

• Estradiol is also present in males, being produced as an active metabolic product of testosterone. The serum levels of estradiol in males (14 - 55 pg/mL) are roughly comparable to those of postmenopausal women (< 35 pg/mL).
  

• Normal estrogen levels in women prior to menopause range from 50 pg/mL to 400 pg/mL.
  
  

• Most men produce 6-8 mg of the male hormone testosterone (an androgen) per day, compared to most women who produce 0.5 mg daily. Female hormones, estrogens, are also present in both sexes, but in larger amounts for women.