[Lotus]

And yes, some estrogens have an increased potential (affinity) for binding to the receptors than others. Hence why in my example of shoe buying I tried to make everything equal, implying that we have the same type of affinity but that whichever one of us gets there first will get the shoes (bind to the receptor) first. Thank you!

Hi Meow,
Thank you for research, I'll admit you're shoe theory is unusual, but I get. It reminds me of Christine Horner's example of the ER car ride,lol

To understand the estrogen pathway better, lets use the analogy of a car ride. Your trip begins in the ovaries where estrogen is made and then is released into the blood. The blood vessels are like highways and estrogen flows through these blood vessel highways to get to its target destinations. When estrogen travels in the blood, it either travels alone or is attached to a substance called a "protein binder" (HSBG, Human Sex Binding Globulin), -the difference between driving alone and carpooling. When you carpool in certain cities, you can use a special high-speed lane, usually on the far left. In this lane, you can't exit from the highway. If you're driving alone, you can't use these high-speed lanes. You must travel in lanes that have access to exit lanes. Like the person driving alone, only the estrogen that travels alone – without a protein binder, SHBG – can exit from the blood-vessel highway. In this case, we are concerned about the off-ramp for only one destination: the breast tissue.

http://www.womenswellnessconsulting.com/pro_active_protocol/estrogen_101/index.html


Here's the correct site from science direct : http://www.phytomedicinejournal.com/article/S0944-7113(13)00275-4/abstract

Btw, you have lovely breasts, can I recommend that you start your own thread?, you'd bring a unique perspective and the citational psychopath would be a great addition, I'd be more then happy to share with you!


Sorry Jesse!, hope you don't mind us sharing from you're op!