Posts: 3
Threads: 1
Joined: Nov 2025
Hi all!
I've been taking BO and pituitary since (fenugreek and maca a few weeks after) December 2025 and I've recently gotten on spironolactone.
Does anyone know if BO diminishes the effects of the anti androgen? What about when I start estradiol?
Anyone who started HRT please let me know their experience ?
Posts: 89
Threads: 1
Joined: Jan 2026
I'm sure some of the ladies here can answer this for sure but if your profile picture is you your got a great figure happening welcome
Posts: 3,111
Threads: 131
Joined: Mar 2012
(5 hours ago)phatasssisssy Wrote: Hi all!
I've been taking BO and pituitary since (fenugreek and maca a few weeks after) December 2025 and I've recently gotten on spironolactone.
Does anyone know if BO diminishes the effects of the anti androgen? What about when I start estradiol?
Anyone who started HRT please let me know their experience ?
Hello,
Welcome to the forum!
I've never been on BO. However, I started estradiol (oral, 2mg) and spironolactone (50mg) at the same time.
In the end though, oral E and spironolactone wasn't enough to get my hormone levels to cis female levels. Instead, I switched to injectional estradiol cypionate and Eligard to maximize feminization of my body.
Posts: 3
Threads: 1
Joined: Nov 2025
(4 hours ago)Curvyguy Wrote: (5 hours ago)phatasssisssy Wrote: Hi all!
I've been taking BO and pituitary since (fenugreek and maca a few weeks after) December 2025 and I've recently gotten on spironolactone.
Does anyone know if BO diminishes the effects of the anti androgen? What about when I start estradiol?
Anyone who started HRT please let me know their experience ?
I'm sure some of the ladies here can answer this for sure but if your profile picture is you your got a great figure happening welcome
Thanks! My boobs in my pic are a breast plate but the rest is all natural ?
Posts: 3
Threads: 1
Joined: Nov 2025
(4 hours ago)flamesabers Wrote: (5 hours ago)phatasssisssy Wrote: Hi all!
I've been taking BO and pituitary since (fenugreek and maca a few weeks after) December 2025 and I've recently gotten on spironolactone.
Does anyone know if BO diminishes the effects of the anti androgen? What about when I start estradiol?
Anyone who started HRT please let me know their experience ?
Hello,
Welcome to the forum!
I've never been on BO. However, I started estradiol (oral, 2mg) and spironolactone (50mg) at the same time.
In the end though, oral E and spironolactone wasn't enough to get my hormone levels to cis female levels. Instead, I switched to injectional estradiol cypionate and Eligard to maximize feminization of my body.
Thanks girl!
I started with 100mg spiro and will go on estradiol in 2 months after next bloodwork. Its my doctor's strategy to lower the first then introduce E, which I'm happy with so long as my herbal routine doesn't diminish their effects.
Posts: 3,111
Threads: 131
Joined: Mar 2012
Your welcome!
The highest I got with spiro was 200mg. Unfortunately, it wasn't effective enough with lowering my testosterone levels.
What form of estradiol will you be starting?
I hope your bloodwork starts to look favorable with your next testing.
I never mixed NBE with HRT. I finished taking PM one day, and the next day I started on oral E and spiro.
