[Lotus]

To be honest the answers are out there, either yet to be discovered in a lab or by our efforts here (meaning people here at BN sharing lab reports). And, as we learn how to analyze them, the analysis (albeit unscientific) helps us all in improving breast growth.

Think about it, scienctists have mapped how we metabolise medications, specificially, the P450 family of enzymes. So, we already identified a few of them here, (green tea, lemons, oranges, red pigmented fruits and veggies, others too). The point being, if we're able to correctly map, (say....white peony as an example), we now know it inhibits 5 ar in the sebaceous gland (DHT), and promote aromatase. But, how is metabolized in breast tissue, is it more pro ER-alpha or beta?, etc. meaning, how is FG, angus cactus (vitex) and others benefiting NBE.

Many other possibilities lol. But, it'll have to wait, going to sleep. I'll be dreaming of a booty like a Cadillac.

[Lotus]

Greetings fellow boobie lovers,

Curious & important question,...........anybody taking Metformin?

[The First Aria]

Greetings fellow boobie lovers,

Curious & important question,...........anybody taking Metformin?

Never heard of it...

[myboobs]

Greetings fellow boobie lovers,

Curious & important question,...........anybody taking Metformin?

What's that ?

[Lotus]

Metformin is a drug that is prescribed to treat type 2 diabetes. It works by decreasing the amount of sugar made by the liver and decreasing the amount of sugar absorbed into the body. As a result, metformin can help the body respond better to its own insulin and decrease blood sugar levels. http://diabetes.emedtv.commetformin/metformin.html

[Lotus]

Here's my point, sugar feeds DHT. When blood sugar is reduced, it reduces DHT. This study below shows that when using a diabetes drug to treat type II diabetes (metformin) it lowered free T (FT) and total T (TT). The point being, say you have type II diabetes and are pursuing NBE and are overweight (yes, it happens), well, the act of lowering blood sugars lowers androgens. A double whammy (of AA's) if you already have anti androgens in your plan. This does tell us that increased blood sugars reduce NBE, and alternately, lower androgens by reducing blood sugars.

Imo, reducing TT and FT is reducing DHT's capacity for production.


The effects of metformin and diet on plasma testosterone and leptin levels in obese men.
Ozata M1, Oktenli C, Bingol N, Ozdemir IC.
Author information
1Department of Endocrinology and Metabolism, Gulhane School of Medicine, Etlik-Ankara, Turkey. mozata@obs.gata.edu.tr
Abstract
OBJECTIVE:
The aim of this study was to investigate the effects of combined hypocaloric diet and metformin on circulating testosterone and leptin levels in obese men with or without type 2 diabetes.
RESEARCH METHODS AND PROCEDURES:
Twenty obese men with type 2 diabetes (mean body mass index [BMI]: 35.5 +/- 1.1 kg/m(2)) and 20 nondiabetic obese men were enrolled in the study. We measured serum follicle-stimulating hormone, luteinizing hormone (LH), total testosterone (TT), free testosterone (FT), sex-hormone-binding globulin (SHBG), dehydroepiandrosterone sulfate (DHEAS), and plasma leptin levels before and 3 months after metformin treatment. Both groups were placed on a hypocaloric diet and 850 mg of metformin taken orally twice daily for 3 months.
RESULTS:
Metformin and hypocaloric diets led to decreases in BMI and waist and hip circumferences in both groups. A significant decrease in TT levels in the diabetic group and FT levels in the control group was found, whereas follicle-stimulating hormone, LH, and DHEAS levels were not changed significantly. A significant increase in SHBG levels was observed in the control group but not in the patient group. Leptin levels also decreased after treatment in both groups. Decreased testosterone levels were not correlated to changes in waist and hip circumference, waist-to-hip ratio, BMI, and levels of fasting blood glucose, leptin, SHBG, or DHEAS in the diabetic group. However, a decrease in FT was correlated to changes in the levels of SHBG (r = -0.71, p = 0.001) and LH (r = 0.80, p = 0.001) but not to other parameters.
DISCUSSION:
We conclude that metformin treatment combined with a hypocaloric diet leads to reduced FT levels in obese nondiabetic men and to reduced TT levels in obese men with type 2 diabetes. Increased SHBG levels may account for the decrease in FT levels in the former group.
PMID: 11707532 [PubMed - indexed for MEDLINE]


Here's more info that Eve shared earlier.
Sugar, Testosterone and DHT
http://www.breastnexus.com/showthread.php?tid=25592

[pom19]

Well Lotus, then why all fat people-both males and females have large breasts? These people are loaded with sugar. That's why they are fat. Their food converts into sugar in their body and gives them too much calories which they do not burn and it turns into fat.

[charrr]

Pshew! So... much... interesting information! (Tongue hangs out) One of your personalities was threatening your retirement from the forum and now- this! Is it revenge?!

[The First Aria]

Well Lotus, then why all fat people-both males and females have large breasts? These people are loaded with sugar. That's why they are fat. Their food converts into sugar in their body and gives them too much calories which they do not burn and it turns into fat.

It's been my observation that bigger people have more problems with diabetes. And, of course more overall body fat will give you bigger breasts, as a general rule. But, not all big people have that disease but are simply more likely.

[Lotus]

Pshew! So... much... interesting information! (Tongue hangs out) One of your personalities was threatening your retirement from the forum and now- this! Is it revenge?!

shoots from downtown and swoosh, it's a 3 pointer lol, my other personalty?, oh yeah, she's one crazy biatch you know, probably created by NBE (lol, well....it could be??, you never know) , she's all about the need for speed, @ boobie science, and aspirations in TG clinical research.....