11-02-2016, 10:13 PM
(07-02-2016, 04:10 AM)MarcyAno Wrote: "I could have had a V8!"
"Lycopene is a natural antioxidant found primarily in tomatoes and tomato products. It gives tomatoes their red color. Research suggests that diets rich in tomatoes and tomato products may have long-term health benefits. V8® Vegetable Juice contains 17.5mg of lycopene per 8-ounce serving, which is over five times the amount found in a medium-sized tomato."
https://www.campbells.com/v8/faqs/
Thanks Marcy,
Indeed, I'll take one too. as you can see in the study below, lycopene inhibits DHT. Works for me.
autocrine/paracrine loops in the Dunning prostate cancer model.
Siler U1, Barella L, Spitzer V, Schnorr J, Lein M, Goralczyk R, Wertz K.
Author information
* 1DSM Nutritional Products, Human Nutrition and Health, Carotenoid Section, Basel, Switzerland.
Abstract
Epidemiological studies have consistently associated high intakes of lycopene or vitamin E with a reduced prostate cancer risk. Both compounds were tested in the MatLyLu Dunning prostate cancer model to gain insight into the in vivo action of lycopene and vitamin E. Supplementation for 4 weeks with 200 ppm lycopene, 540 ppm vitamin E, or both led to plasma levels comparable with those in humans. Both compounds also accumulated in tumor tissue. Macroscopic evaluation of the tumors by magnetic resonance imaging showed a significant increase in necrotic area in the vitamin E and the lycopene treatment groups. Microarray analysis of tumor tissues revealed that both compounds regulated local gene expression. Vitamin E reduced androgen signaling without affecting androgen metabolism. Lycopene interfered with local testosterone activation by down-regulating 5-alpha-reductase and consequently reduced steroid target genes expression (cystatin-related protein 1 and 2, prostatic spermine binding protein, prostatic steroid binding protein C1, C2 and C3 chain, probasin). In addition, lycopene down-regulated prostatic IGF-I and IL-6 expression. Based on these findings, we suggest that lycopene and vitamin E contribute to the reduction of prostate cancer by interfering with internal autocrine or paracrine loops of sex steroid hormone and growth factor activation/synthesis and signaling in the prostate.