01-06-2025, 01:05 AM
One thing I’ve been trying to wrap my head around is the actual potency of 0.075mg of norgestrel in Opill. Jessi’s post really hit on something with the comparison to male contraception trials using way higher doses plus testosterone. If they needed that much to see consistent effects, it does make you wonder what kind of threshold actually matters.
Also, for anyone thinking of longer-term use, it might be worth looking at how similar progestins have shown up in other medical contexts. For example, Depo-Provera (which uses a different progestin, medroxyprogesterone) has a history of notable side effects, some of which overlap with what a few folks here have mentioned, like joint pain or dental issues. This page lays it out clearly if you're curious: https://federal-lawyer.com/injury-lawsui...de-effect/.
Anyway, I’m still undecided, but definitely appreciating the real-world experiences here. Please keep them coming.
Also, for anyone thinking of longer-term use, it might be worth looking at how similar progestins have shown up in other medical contexts. For example, Depo-Provera (which uses a different progestin, medroxyprogesterone) has a history of notable side effects, some of which overlap with what a few folks here have mentioned, like joint pain or dental issues. This page lays it out clearly if you're curious: https://federal-lawyer.com/injury-lawsui...de-effect/.
Anyway, I’m still undecided, but definitely appreciating the real-world experiences here. Please keep them coming.