(21-09-2025, 12:34 PM)blackbirdordinary Wrote: Have never seen anyone before suggest Bicalutamide as known more effective for the TransLater crowd. Your voluminous body of (results!) posts here leads me to believe you have more reasons to say that than purely personal experience. Can you share more about bica?
That study of teen trans women, plus the many studies of Bicalutamide in older men who mostly tolerate it very well are all that’s out there. But no studies of older trans women exist.
Am a four year lurker here, 48 year old bigender enby making my first post. Am seeking strong breast growth from my existing base top where I have always experienced gynecomastia, while maintaining bottom function. As a bigender person, the plan is maintaining my assigned gender (m) identity, because is also gender affirming to me. (And yes, I am keenly aware of ED, taladafil, t creams and viagra for the bottom.) At the same time, this is not so much my fear of feminization so much as wanting to express both genders which I identify with fully, wholesomely and without terrible conflict (had enough conflict, thx!).
Haven’t taken anything yet, but had a first visit with my doctor and told them I wanted to try Bicalutamide mono therapy to accomplish these goals. They said it might not be enough for full breast development, but I told them it’s a marathon, not a sprint. Was not actually expecting the Doctor to agree with me so easily as they did.
Can bica alone be enough, for the most part? Any tips from your experience?
Thank you for your many contributions to this board.
Hi! With this I would so much appreciate having Lotus chime in as she would know more than I do. The thing with Bica is that it in itself has a feminising effect on the body on the side of being an excellent T blocker, or should I say receptor blocker as it makes T receptors not react to T. I don't have studies at hand which I could link or quote, but this has to do with the way Bica works and its excellent blocker due to it alone aiding breast developement. This was studies on young trans girls who were on Bica as a puberty blocker and that alone was able to give them noticeable breastdevelopment and feminisation of body which of course is more than welcome for any trans woman.
I have discussed use of Bica as blocker with Lotus, Stevenator, I think with Melissa too and then there's all the positive things I read online and decided to switch from Cypro to Bica and my body changes since then have taken an uptick, especially breasts and face changes. Small dose of 25mg twice a week is well enough to block T and it doesn't seem to be harmful to my liver either, tiny doses should have very little side ffect margin so its likely to be very safe used like this.
You are correct, studies on older trans women do not exist as bica isn't prescribed often to anyone older than thirty in my knowledge.
I'm convinced that Bica is effective on its own, as when I started it I didn't make any major changes to my HRT and NBHE programs, but my body changes took quite a leap in rather short time and its still on going, right now better than ever about which I just posted in my main thread.
I would be quite confident about trying Bica as monotherapy, just make sure the doses stay moderate as Bica can be very stressful to liver, but afaik only if the doses are quite high.