For four years I have been using Herbs and Creams ,you name it I have tried it but with poor results ,probably due to my age,three months ago I started on Progesterone/Estrogen 20 to 1 ,2 jars @2.i oz. each,the results have been very encouraging and no change to my well being ,probably due to the low dosage,I have restarted with the same,hoping this will fill out what I have already achieved,will keep you posted as time goes by.