I've done as much research as I can on this topic. I've looked at the various cytokines and pharmacokinetics involved. It seems reasonably safe. Anyone have specific info on how various doses affect the liver or have any particular info on this subject?
I'm not sure. But for any powder, a lot of water is needed. Any food causes the liver work, and powdered form is even a lot more work for it.
The extract will escape much of the first pass metabolism if liver function is a concern. Sublingual delivery is 98%, transdermal is 60%.
General averages of rates/ratios when consuming herbs
Q-
How long does a capsule take to dissolve?
A-Typically the average is up to 20 minutes, some sources have at 5-10 minutes while others say 20-30 minutes. Extracts 1 to 4 minutes
Q-
What are typical absorption results?
A-For skin application- 60%
A-Liquid- 98%
A-capsule- 10-20%
Q-
What is the capsule to extract ratio?
A- 20 to 1, meaning it would take 20 capsules to = 1 teaspoon of extract
Q-
When is the best time to take an herb?
A-In general, herbs are best taken on an empty stomach
When to supplement (timing)
-------------------------------------------------------------
Hormones are released every 90 minutes, the binding of receptors takes 30-45 minutes upon activation. The process of supplementing should match that cycle (e.g. supplement every 4 hrs to correspond with the cycle rather than taking all at once, or in large dose).
And if inflammation is a concern look into Green Tea, and omega 3's-
Polyphenols (specifically Green Tea) promotes aromatase, anti-oxidation, estrogen, modifies signaling transduction pathways, relieves oxidative stress (reduces lipid oxidation), possess potent iron-chelating radical-scavenging and anti-inflammatory activities (polyphenols are powerful free radical destroyers), protects against neurological diseases. Green tea catechins ameliorate adipose insulin resistance.
Thanks Lotus for the INFO, very useful. POM
I am going to nick name Lotus... The Guru of Breast Nexus. Catchy, eh??
(05-02-2015, 09:49 PM)iaboy Wrote: [ -> ]I am going to nick name Lotus... The Guru of Breast Nexus. Catchy, eh??
--------------------------------------------------
Well, while back I called him "Hormone Scientist." POM
Hmmm, maybe we should do a Poll??? Just to get his title an air of being official????
(05-02-2015, 10:01 PM)iaboy Wrote: [ -> ]Hmmm, maybe we should do a Poll??? Just to get his title an air of being official????
---------------------------------------------------------------
How about any title, as long as is good.
Nah, cause I am just devil enough to razz him.