Glad to see a new Lotus post, first time i see one while i registered on this forum.
I have no doubts on the new low risk breast growth plan, of course there are lots of researches about it and Lotus always posts facts, but one thing which has give me questions is the complete absence of any herbal estrogenic source. Isn't it necessary anymore? Is this plan more similar to a pharma hrt program with an hospital doctor or still can be considered NBE? Not sure because those estriol and progesterone cream seems medications which needs a prescription. I'm confused.
(28-01-2021, 04:23 PM)Alexis P Wrote: [ -> ]Glad to see a new Lotus post, first time i see one while i registered on this forum.
I have no doubts on the new low risk breast growth plan, of course there are lots of researches about it and Lotus always posts facts, but one thing which has give me questions is the complete absence of any herbal estrogenic source. Isn't it necessary anymore? Is this plan more similar to a pharma hrt program with an hospital doctor or still can be considered NBE? Not sure because those estriol and progesterone cream seems medications which needs a prescription. I'm confused.
Hi Alexis, not sure about Italy/EU, but in the US you can find low-dose Estrogen and Progesterone creams (over the counter, or OTC as Lotus uses above) in pharmacies and online. They are generally lower dose (1-10% the amount of hormone) than what you would get with HRT, designed to help women who are dealing with post-menopausal issues or estrogen dominance.
Because the doses will be a lot lower than prescription HRT patches, any effects will take a lot longer to be seen. But because its trans-dermal, and estradiol rather than phytoestrogens (as in PM), likely to have fewer side effects (e.g. safer). This one for example, as .5 mg estradiol per pump, while the standard of care for trans HRT is going to be 2-4 mg/day estradiol orally.
https://www.amazon.com/dp/B07DFVL6WD/ref...FQXQ2E7E1N
I think the thing to note about creams is the absorbed amount obviously varies based on the amount you apply and where you apply it. From what I’ve seen, the amount contained within creams can vary by 10x. So it’s going to be a lot more judgement and ‘do what feels right’ than with PM or supplements, where the dosage is controlled. That said, the amount of hormone is a lot lower too, so the downside risk of over-applying is probably low.
(29-01-2021, 02:53 AM)Stevenator_too Wrote: [ -> ]In this example the man (who's probably older) with a higher BMI (body mass index) would see most of that T injection convert to E (estrogen) by way of the aromatase enzyme...until it could re-establish T
You just called me fat!
Oh snap. I'm gonna go with science on this one and say that's how it's described in science literature.
(28-01-2021, 11:26 AM)Stevenator_too Wrote: [ -> ]The science that Lotus provides makes this site what it is. It separates this site from the others. It’s funny how my psoriasis goes away, when Lotus returns.
Thank you Stevenator, you've been a good to me and this forum.
Hi Lotus, thanks for the kind note - I certainly don’t have the knowledge you do!
I will say your recent thoughts on creams also had me researching a bit. I’m curious about the link between progesterone and lobule/duct development. I’ve seen a number of conflicting research papers: Sonnenblick et al. 2018 seems to indicate HRT with progesterone in men will lead to identical breast structure as cisgender women, while a bunch of others seem to indicate only the fibrous dense tissue is formed in men regardless of HRT regimen. Certainly typical gynocomastia seems to be only dense tissue, so I was curious if the progesterone supplementation is the differentiator for lobule development?
If so, it seems like progesterone would be required not just to further nodule/dense tissue growth, but also to foster lobe/duct development for a ‘full’ breast.
Also curious, have you seen any other research on P/E affecting adipose tissue composition when applied transdermally? I’ve seen recommendations against applying where there is a lot of subcuteneous fat (likely affecting absorption), but am curious if it would have positive growth effects on adipose tissue that is E sensitive? And inversely, if it would impact fat distribution in android regions that is typically more T sensitive?
Thanks much!
It’s good to have you back.