So I asked my gyno for a hormone test & my results were a Vitamin D deficiency. So I've been taking 7,000 units a day as prescribed & my tiny breasts feel a little fuller. Anyone else experience this?
Nothing else in my diet has changed.
I'm new to this journey & the hormone test was my 1st step of action. Now that I'm taking care of that I'm not sure what to do next. Any thoughts/ideas welcome!
(28-06-2015, 01:59 AM)MermaidKisses523 Wrote: [ -> ]So I asked my gyno for a hormone test & my results were a Vitamin D deficiency. So I've been taking 7,000 units a day as prescribed & my tiny breasts feel a little fuller. Anyone else experience this?
Nothing else in my diet has changed.
I'm new to this journey & the hormone test was my 1st step of action. Now that I'm taking care of that I'm not sure what to do next. Any thoughts/ideas welcome!
I'm not sure exactly how this works, but Vitamin D isn't exactly like other vitamins. It's a precursor to a steroid hormone. Oestrogens, androgens, and progestins are also steroid hormones. So I don't know exactly what Vitamin D does, and someone else here could probably shed more light on that, but it's not out of the question that it could impact growth.
Vitamin D, also known as the sunshine vitamin, can be produced in the body with mild sun exposure or consumed in food or supplements.
Adequate vitamin D intake is important for the regulation of calcium and phosphorus absorption, maintenance of healthy bones and teeth, and is suggested to supply a protective effect against multiple diseases and conditions such as cancer, type 1 diabetes and multiple sclerosis.
In spite of the name, vitamin D is not actually considered a vitamin. Because the body can produce its own vitamin D, it is not necessarily an essential part of the diet and is considered a pro-hormone.
It is estimated that sensible sun exposure on bare skin for 5-10 minutes 2-3 times per week allows the body the ability to produce sufficient vitamin D. Despite this, recent studies have suggested that up to 50% of adults and children worldwide are vitamin D deficient.Souce:
http://www.medicalnewstoday.com/articles/161618.php
Whatever you'll take, do not take too much. POM
The bottom line is that vitamin D is a potent aromatase, this is most likely why you feel fullness.
(08-06-2015, 10:01 PM)Lotus Wrote: [ -> ]Vitamin D3 may indirectly affect cAMP production from PGE1 by 5x, in other words, this (D3) will help upregulate aromatase.
1,25DIHYDROXYCHOLECALCIFEROL INDUCES AN INCREASE IN PGE 1 - AND FORSKOLIN-STIMULATED CYCLICAMP PRODUCTION IN T47D HUMAN BREAST CANCER CELL LINE
ABSTRACT — The effect of 1, 25-dihydroxycholecalciferol [1, 25(OH)2 D3], the active form of vitamin D3, on cell growth, clonogenicity, and cyclic adenosine monophosphate (cAMP) production was examined in human breast cancer cell line T47D. 1,25(OH)2 D3 markedly inhibited proliferation of T47D cells in a time- and concentration-dependent manner. 1,25(OH)2 D3 5 times 10−7 reduced to 70% [3H]thymidine incorporation into DNA. Specific high affinity nuclear receptors for 1,25(OH)2 D3 were present in this cell line. The cAMP produced by T47D cells was measured during 10 min stimulation by effectors (prostaglandin E1 or forskolin). Without effector, T47D cells produced similar amounts of cAMP in control and 1,25(OH)2 D3-treated cells. After 3 days in the presence of 1,25(OH)2 D3, cAMP production was significantly increased compared to control cells when stimulated by 10−4 M prostaglandin E1 or 5 times 10−7 M forskolin (3.2- and 2.4-fold increase, respectively). This cAMP increase was concentration dependent within the same range that inhibited cell growth and clonogenicity. These results suggest that 1,25(OH)2 D3 may indirectly affect cAMP production by modulating the target cell response to stimulatory agents of cAMP production.
http://www.researchgate.net/publication/..._CELL_LINE
vitamin D analogs significantly upregulated E2- and DHT-induced CK response. These analogs upregulated the CK response to selective estrogen receptor modulators (SERMs). An estrogenic response (from vitamin D) is seen in the intestinal tract. Vitamin D also helps with hair growth.
http://www.howtomakeyourhairgrowfast.net...rowth.html
Interaction Between Estrogen and Vitamin D–Endocrine System: A Potential Addition to the Unitary Model of Osteoporosis
http://onlinelibrary.wiley.com/doi/10.13....1954/full
Vitamin D modulation of the activity of estrogenic compounds in bone cells in vitro and in vivo.
Somjen D1.
Author information
Abstract
Vitamin D analogs modulate different organs, including modulation of energy metabolism, through the induction of creatine kinase (CK) activity. Skeletal organs from vitamin D-depleted rats showed lower constituent CK than those from vitamin D-replete rats. Moreover, estradiol-17beta (E2) or dihydrotestosterone (DHT), which increased CK in organs from intact female or male rats, respectively, stimulated much less CK in vitamin D-depleted rats. Treatment of intact female rats with noncalcemic vitamin D analogs significantly upregulated E2- and DHT-induced CKresponse.
These analogs upregulated the CK response to selective estrogen receptor modulators (SERMs) in organs from intact or ovariectomized (Ovx) female rats but abolished SERMs' inhibitory effect on E2-induced CK.
These analogs significantly increased estradiol receptor alpha (ERalpha) protein in skeletal organs as well as histomorphological and biochemical changes due to this treatment followed by E2 or DHT. The analogs alone markedly altered the growth plate and the trabeculae and increased trabecular bone volume (%TB V) and trabecular width. The addition of E2 or DHT to this treatment restored all parameters as well as increased %TBV and cell proliferation. Treatment of Ovx female rats with JK 1624 F2-2 (JKF) decreased growth-plate width and increased %TB V, whereas QW1624 F2-2 (QW) restored growth-plate width and %TB V. Treatment of E2 with JKF restored %TBV and growth-plate width, whereas E2 with QW restored all parameters, including cortical width. There was also upregulation of the response of CK to E2 in both combined treatments. Our human-derived osteoblast (hObs)-like cell cultures respond to estrogenic compounds, and pretreating them with JKF upregulated the CK response to E2, raloxifene (Ral), and some phytoestrogens. ERalpha and ERbeta proteins, as well as mRNA, were modulated by CB 1093 (CB) and JKF.
JKF increased specific nuclear E2 binding in female hObs but inhibited specific membranal E2 binding. hObs express 25 hydroxyvitamin D3-1alpha hydroxylase (1-OHase)-mRNA and its biological activity, which are both modulated by parathyroid hormone (PTH) and estrogenic compounds. Our results demonstrate mutual interaction between vitamin D and estrogenic compounds. We therefore conclude that combined treatment with less-calcemic analogs of vitamin D and estrogenic compounds might be superior for treatment of bone damage caused by ovariectomy in female rats, with possible application for postmenopausal osteoporosis.
PMID: 17725484 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/17725484
Thanks for this info Lotus. POM
I'm always dumbstruck when I read of the benefits of vit d.
It's role in disease prevention is incredible and how funny we are all encouraged to lather up on sunscreen to block sunshine and taught to fear the sun.
I've even read sun gazing at the appropriate time around sunset is pused to treat Disease, I wonder if the eyes absorb vit d more effeicently or equal to the skin.
That's interesting re the boost in breasts, it reminded me my levels were bordering low when tested last year.
One thing though mer cola says to take vit k2 when consuming high amounts of vit d3? And I'd assume anything over 1000mg would be considered high. They say therapeutic doses can go up to 10,000mg. My tabs are 5000mg but I take them every second day when I remember.
Thanks Lotus!! I'm already taking vitD to recover from my accident. But last time I bought it I got confused because there are three forms.
Water soluble(aquosum), Oil soluble and just tablets. I know that I have to choose for liquid form thats better with vitD then the pillform but which of the 2 is better, IDK. Done some research but remained unclear except for the part that liquid is better then pill.
(30-06-2015, 02:43 PM)hannah14 Wrote: [ -> ]Thanks Lotus!! I'm already taking vitD to recover from my accident. But last time I bought it I got confused because there are three forms.
Water soluble(aquosum), Oil soluble and just tablets. I know that I have to choose for liquid form thats better with vitD then the pillform but which of the 2 is better, IDK. Done some research but remained unclear except for the part that liquid is better then pill.
Any vit d3 I ever brought comes in a gel cap with liquid inside
(30-06-2015, 07:36 PM)ELLACRAIG Wrote: [ -> ] (30-06-2015, 02:43 PM)hannah14 Wrote: [ -> ]Thanks Lotus!! I'm already taking vitD to recover from my accident. But last time I bought it I got confused because there are three forms.
Water soluble(aquosum), Oil soluble and just tablets. I know that I have to choose for liquid form thats better with vitD then the pillform but which of the 2 is better, IDK. Done some research but remained unclear except for the part that liquid is better then pill.
Any vit d3 I ever brought comes in a gel cap with liquid inside
Mines are in a dropper. But the other ones seriously came in a pill..I still have them here but dont use them often.
(30-06-2015, 07:44 PM)hannah14 Wrote: [ -> ] (30-06-2015, 07:36 PM)ELLACRAIG Wrote: [ -> ] (30-06-2015, 02:43 PM)hannah14 Wrote: [ -> ]Thanks Lotus!! I'm already taking vitD to recover from my accident. But last time I bought it I got confused because there are three forms.
Water soluble(aquosum), Oil soluble and just tablets. I know that I have to choose for liquid form thats better with vitD then the pillform but which of the 2 is better, IDK. Done some research but remained unclear except for the part that liquid is better then pill.
Any vit d3 I ever brought comes in a gel cap with liquid inside
Mines are in a dropper. But the other ones seriously came in a pill..I still have them here but dont use them often.
I figured its kinda the same thing, liquid in a gel cap but either way I think they both would be effective as long as we can avoid fillers etc in either.
So your dr prescribed vit d for that car accident you had? that's interesting, what was their reason for doin it?